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    Community grid management is an important measure to contain the spread of novel coronavirus pneumonia (COVID-19). Ling Chen,Wen Xianjie Epidemiology and infection The outbreak of novel coronavirus pneumonia (coronavirus disease 2019 (COVID-19)), declared as a 'global pandemic' by the World Health Organization (WHO), is a public health emergency of international concern (PHEIC). The outbreak in multiple locations shows a trend of accelerating spread around the world. China has taken a series of powerful measures to contain the spread of the novel coronavirus. In response to the COVID-19 pandemic, in addition to actively finding effective treatment drugs and developing vaccines, it is more important to identify the source of infection at the community level as soon as possible to block the transmission path of the virus to prevent the spread of the pandemic. The implementation of grid management in the community and the adoption of precise management and control measures to reduce unnecessary personnel movement can effectively reduce the risk of pandemic spread. This paper mainly describes that the grid management mode can promote the refinement and comprehensiveness of community management. As a management system with potential to improve the governance ability of community affairs, it may be helpful to strengthen the prevention and control of the epidemic in the community. 10.1017/S0950268820001739
    Smell and taste dysfunction in patients with COVID-19. Xydakis Michael S,Dehgani-Mobaraki Puya,Holbrook Eric H,Geisthoff Urban W,Bauer Christian,Hautefort Charlotte,Herman Philippe,Manley Geoffrey T,Lyon Dina M,Hopkins Claire The Lancet. Infectious diseases 10.1016/S1473-3099(20)30293-0
    Olfactory Dysfunction in COVID-19: Diagnosis and Management. Whitcroft Katherine Lisa,Hummel Thomas JAMA 10.1001/jama.2020.8391
    Real-time tracking of self-reported symptoms to predict potential COVID-19. Menni Cristina,Valdes Ana M,Freidin Maxim B,Sudre Carole H,Nguyen Long H,Drew David A,Ganesh Sajaysurya,Varsavsky Thomas,Cardoso M Jorge,El-Sayed Moustafa Julia S,Visconti Alessia,Hysi Pirro,Bowyer Ruth C E,Mangino Massimo,Falchi Mario,Wolf Jonathan,Ourselin Sebastien,Chan Andrew T,Steves Claire J,Spector Tim D Nature medicine A total of 2,618,862 participants reported their potential symptoms of COVID-19 on a smartphone-based app. Among the 18,401 who had undergone a SARS-CoV-2 test, the proportion of participants who reported loss of smell and taste was higher in those with a positive test result (4,668 of 7,178 individuals; 65.03%) than in those with a negative test result (2,436 of 11,223 participants; 21.71%) (odds ratio = 6.74; 95% confidence interval = 6.31-7.21). A model combining symptoms to predict probable infection was applied to the data from all app users who reported symptoms (805,753) and predicted that 140,312 (17.42%) participants are likely to have COVID-19. 10.1038/s41591-020-0916-2
    Olfactory and Gustatory Dysfunction as an Early Identifier of COVID-19 in Adults and Children: An International Multicenter Study. Qiu Chenghao,Cui Chong,Hautefort Charlotte,Haehner Antje,Zhao Jun,Yao Qi,Zeng Hui,Nisenbaum Eric J,Liu Li,Zhao Yu,Zhang Di,Levine Corinna G,Cejas Ivette,Dai Qi,Zeng Mei,Herman Philippe,Jourdaine Clement,de With Katja,Draf Julia,Chen Bing,Jayaweera Dushyantha T,Denneny James C,Casiano Roy,Yu Hongmeng,Eshraghi Adrien A,Hummel Thomas,Liu Xuezhong,Shu Yilai,Lu Hongzhou Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery OBJECTIVE:To evaluate the prevalence and characteristics of olfactory or gustatory dysfunction in coronavirus disease 2019 (COVID-19) patients. STUDY DESIGN:Multicenter case series. SETTING:Five tertiary care hospitals (3 in China, 1 in France, 1 in Germany). SUBJECTS AND METHODS:In total, 394 polymerase chain reaction (PCR)-confirmed COVID-19-positive patients were screened, and those with olfactory or gustatory dysfunction were included. Data including demographics, COVID-19 severity, patient outcome, and the incidence and degree of olfactory and/or gustatory dysfunction were collected and analyzed. The Questionnaire of Olfactory Disorders (QOD) and visual analog scale (VAS) were used to quantify olfactory and gustatory dysfunction, respectively. All subjects at 1 hospital (Shanghai) without subjective olfactory complaints underwent objective testing. RESULTS:Of 394 screened subjects, 161 (41%) reported olfactory and/or gustatory dysfunction and were included. Incidence of olfactory and/or gustatory disorders in Chinese (n = 239), German (n = 39), and French (n = 116) cohorts was 32%, 69%, and 49%, respectively. The median age of included subjects was 39 years, 92 of 161 (57%) were male, and 10 of 161 (6%) were children. Of included subjects, 10% had only olfactory or gustatory symptoms, and 19% had olfactory and/or gustatory complaints prior to any other COVID-19 symptom. Of subjects with objective olfactory testing, 10 of 90 demonstrated abnormal chemosensory function despite reporting normal subjective olfaction. Forty-three percent (44/102) of subjects with follow-up showed symptomatic improvement in olfaction or gustation. CONCLUSIONS:Olfactory and/or gustatory disorders may represent early or isolated symptoms of severe acute respiratory syndrome coronavirus 2 infection. They may serve as a useful additional screening criterion, particularly for the identification of patients in the early stages of infection. 10.1177/0194599820934376
    Persistent Smell Loss Following Undetectable SARS-CoV-2. Yan Carol H,Prajapati Divya P,Ritter Michele L,DeConde Adam S Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery The association of smell and taste loss with COVID-19 has been well demonstrated with high prevalence rates. In certain cases, chemosensory loss may be the only symptom of COVID-19 and may linger while other symptoms have resolved. The significance of persistent smell and taste loss and its relationship to ongoing viral shedding has yet to be investigated. In this cross-sectional study, of the 316 laboratory test-confirmed COVID-19 cases at our institution, 46 had subsequent test-based confirmation of viral clearance with 2 consecutive negative RT-PCR test results (reverse transcriptase polymerase chain reaction). Olfactory dysfunction was reported by 50% of the patients (23 of 46), with 78% (18 of 23) having subjective persistent smell loss despite negative RT-PCR test results. These preliminary data demonstrate the persistence of self-reported smell loss despite otherwise clinical resolution and undetectable nasal viral RNA. 10.1177/0194599820934769
    Objective olfactory evaluation of self-reported loss of smell in a case series of 86 COVID-19 patients. Lechien Jerome R,Cabaraux Pierre,Chiesa-Estomba Carlos M,Khalife Mohamad,Hans Stéphane,Calvo-Henriquez Christian,Martiny Delphine,Journe Fabrice,Sowerby Leigh,Saussez Sven Head & neck OBJECTIVE:To investigate olfactory dysfunction (OD) in patients with mild coronavirus disease 2019 (COVID-19) through patient-reported outcome questionnaires and objective psychophysical testing. METHODS:COVID-19 patients with self-reported sudden-onset OD were recruited. Epidemiological and clinical data were collected. Nasal complaints were evaluated with the sinonasal outcome-22. Subjective olfactory and gustatory status was evaluated with the National Health and Nutrition Examination Survey. Objective OD was evaluated using psychophysical tests. RESULTS:Eighty-six patients completed the study. The most common symptoms were fatigue (72.9%), headache (60.0%), nasal obstruction (58.6%), and postnasal drip (48.6%). Total loss of smell was self-reported by 61.4% of patients. Objective olfactory testings identified 41 anosmic (47.7%), 12 hyposmic (14.0%), and 33 normosmic (38.3%) patients. There was no correlation between the objective test results and subjective reports of nasal obstruction or postnasal drip. CONCLUSION:A significant proportion of COVID-19 patients reporting OD do not have OD on objective testing. 10.1002/hed.26279