Influence of dietary fat source on sow and litter performance, colostrum and milk fatty acid profile in late gestation and lactation. Jin Chao,Fang Zhengfeng,Lin Yan,Che Lianqiang,Wu Caimei,Xu Shengyu,Feng Bin,Li Jian,Wu De Animal science journal = Nihon chikusan Gakkaiho The objective of this study was to investigate the effects of dietary supplementation with various fat sources (3.8-3.9% of diet) during late pregnancy and lactation on the reproductive performance, fatty acids profile in colostrum, milk and serum of sow progeny. A total of 80 multiparous sows were randomly fed a control (adding no oil), palm oil (PO), fish oil (FO) or soybean oil (SO) supplemented diet from 90 days of pregnancy to weaning. Supplementation of FO increased litter size of weak piglets, compared with the control-fed sows (P < 0.05). Dietary FO and SO supplementation, enhanced the weaning survival rate, litter weaning weight, litter weight gain and fat content in milk (P < 0.05). The highest immunoglobulin (Ig)G and IgM levels in colostrum and milk were observed in the FO group (P < 0.05). Meanwhile, the highest concentration of C22:5 (n-3) and C22:6 (n-3) in colostrum, milk and piglet serum was observed in the FO group (P < 0.05). Taken together, dietary inclusion of FO or SO improved growth performance of nursing piglets by increasing milk fat output, and FO consumption by sows might benefit the piglets via increasing n-3 polyunsaturated fatty acid availability and immunoglobulins (IgG and IgM) secretion. 10.1111/asj.12836

Dynamic changes of fatty acids and minerals in sow milk during lactation. Hu Ping,Yang Huairong,Lv Bo,Zhao Daoyuan,Wang Jing,Zhu Weiyun Journal of animal physiology and animal nutrition The objective of the present study was to explore the changes in fatty acids (FAs) and minerals composition in sow milk in order to improve the knowledge about FAs and mineral requirements for piglets. The FAs and minerals composition in the sow milk samples which were collected from ten sows during a period of 16 days of lactation was analysed. The proportion of FAs in sow milk has a significant increase in C8:0, C10:0, C12:0, C14:0, C16:0, C14:1 and C16:1 FAs and the sum of saturated fatty acids (SFAs) according to the lactation period (p < 0.05). The proportion of C18:2 cis-9,12 FA and the sum of polyunsaturated fatty acids (PUFAs) significantly decreased with the advancing of lactation (p < 0.05). The concentrations of minerals, including potassium, copper, manganese and zinc, were higher on day 1 and day 2 than those on day 13 and day 16 (p < 0.05). On the contrary, the lowest concentrations of calcium, sodium, magnesium and iron and the lowest molar calcium: phosphorus ratio emerged in colostrum (p < 0.05). In summary, our results demonstrated FAs profile and minerals concentrations were changed with lactation period. Better understanding of the changes of FAs and minerals may be valuable to swine nutritionists in the commercial industry. In addition, those results provided some meaningful information for sow's diet formulation during lactation. 10.1111/jpn.13040

Increasing selenium supply for heat-stressed or actively cooled sows improves piglet preweaning survival, colostrum and milk composition, as well as maternal selenium, antioxidant status and immunoglobulin transfer. Chen Jun,Zhang Fangting,Guan Wutai,Song Hanqing,Tian Min,Cheng Lin,Shi Kui,Song Junshuai,Chen Fang,Zhang Shihai,Yang Fei,Ren Chunxiao,Zhang Yinzhi Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) This study aimed to evaluate the effects of increasing selenium (Se) supply for heat-stressed or actively cooled sows on sow productivity, colostrum and milk composition, as well as the selenium and antioxidant status and immunoglobulin levels of sows and nursing piglets. The study was a 2 × 2 factorial design, where the first factor was farrowing environment [heat stress vs. actively cooling, temperature: 29.61 ± 0.19 ℃ (27.70-31.60 ℃) vs. 27.90 ± 0.15 ℃ (26.90-30.20 ℃); temperature-humidity index: 72.91 ± 0.26 (70.30-75.70) vs. 70.81 ± 0.22 (69.30-73.80)], and the second factor was dietary Se level during late gestation and lactation [(0.3 vs. 1.2 mg/kg Se as Se-yeast, the basal diet was corn-soybean meal diet formulated according to NRC (2012) except for Se level]. Forty multiparous sows (Landrace × Yorkshire) were randomly allotted to 1 of 4 treatments (10 sows and following 90 piglets per treatment, respectively). The results show that: (1) There were no interactions of farrowing environment with Se treatments with the exceptions of nutrient content of 7-d milk; (2) As for zootechnical measures, piglets of sows receiving increasing Se tended to have greater preweaning survival compared with those of sows receiving control diet without interactions of environment and Se treatments; (3) As to colostrum and milk composition, greater concentrations of protein, lactose, solids-not-fat in colostrum, and greater fat concentration in 7-d and 14-d milk were found for sows fed increasing Se; (4) Regarding Se and antioxidant status, increasing Se supply for sows increased Se content in colostrum and 21-d milk, as well as in plasma of 1-day-old and 21-day-old piglets. Meanwhile, increasing Se supply for sows improved antioxidant status in colostrum (MDA content) and 21-d milk (T-AOC and MDA content), as well as in plasma of 1-day-old and 21-day-old piglets (GSH-Px activity and MDA content); (5) With regard to immunoglobulins, sows fed increasing Se had higher IgM levels in colostrum, and higher IgA in 21-d milk. Also, piglets from sows fed increasing Se had higher plasma IgA at 1 d of age, and higher IgA and IgG levels at 21 d of age. Collectively, increasing selenium supply for heat-stressed or actively cooled sows improved piglet preweaning survival, colostrum and milk composition, as well as maternal selenium, antioxidant status and immunoglobulin transfer irrespective of the climatic conditions, which indicates that Se requirements for sows should be urgently reassessed. 10.1016/j.jtemb.2018.11.010

Review: nutritional and endocrine control of colostrogenesis in swine. Quesnel H,Farmer C Animal : an international journal of animal bioscience Colostrum plays an essential role in ensuring the survival, growth and health of piglets by providing energy, nutrients, immunoglobulins, growth factors and many other bioactive components and cells. Both colostrum yield and composition are highly variable among sows, yet mechanisms and factors that regulate colostrogenesis are not fully known. Unlike sow milk yield, sow colostrum yield is not highly determined by litter size and suckling intensity but is largely driven by sow-related factors. Colostrum synthesis is under hormonal control, with prolactin and progesterone concentrations prepartum having, respectively, positive and negative influences on colostrum yield. Less is known about the endocrine control of the end of colostrogenesis in swine, which is characterized by the closure of tight junctions in the mammary epithelium and the cessation of transfer of immunoglobulin G (IgG) into lacteal secretions. Recent studies indicate that exogenous hormones may influence colostrogenesis. Inducing parturition by injecting prostaglandin F2α on day 114 of gestation in combination with an oxytocin-like molecule reduced colostrum yield, and injection of prostaglandin F2α alone either reduced colostrum yield or had no effect. Injecting a supraphysiological dose of oxytocin to sows in the early postpartum period delayed the tightening of mammary tight junctions, thereby prolonging the colostral phase and increasing concentrations of IGF-I and IgG and IgA in early milk. The development of strategies to improve colostrum composition in swine through maternal feeding has been largely explored but very few attempts were made to increase colostrum yield. This is most likely because of the difficulty in measuring colostrum yield in swine. The fatty acid content of colostrum greatly depends on the amount of lipids provided in the sow diet during late gestation, whereas the fatty acid profile is largely influenced by the type of lipid being fed to the pregnant sow. Moreover, various ingredients that presumably have immuno-modulating effects (such as fish oil, prebiotics and probiotics) increased concentrations of IgG, IgA and/or IgM in sow colostrum when they were provided during the last weeks of gestation. Finally, there is some evidence that sow nutrition during late gestation may influence colostrum yield but this clearly warrants more research. This review emphasizes that although progress has been made in understanding the control of colostrogenesis in swine, and that strategies exist to manipulate fat and immunoglobulin contents of colostrum, ways to increase colostrum yield are still lacking. 10.1017/S1751731118003555

Phytogenic actives supplemented in hyperprolific sows: effects on maternal transfer of phytogenic compounds, colostrum and milk features, performance and antioxidant status of sows and their offspring, and piglet intestinal gene expression. Journal of animal science Phytogenic actives (PA) are plant-derived natural bioactive compounds that may promote livestock health and well-being, as well as improve growth performance and production efficiency. The current study aims to evaluate their effects on sows and their offspring. Eighty-one hyperprolific sows (up to parity 7) were assigned to 3 experimental treatments. Control sows were offered a nonsupplemented diet during gestation and lactation, and treated sows were fed the control diet supplemented with 1 g/kg of a blend of PA (BPA) in lactation (L) or during gestation and lactation (GL). An evaluation was made of placental and milk maternal transfer of these BPA and colostrum-milk features, sows and piglets antioxidant status, reproductive performance (litter size), body weight (BW) changes, weaning-estrus interval, and litter performance. Finally, piglet´s jejunum gene expression was measured. The BPA supplementation during gestation (GL) increased the number of piglets born alive (P = 0.020) and reduced (P < 0.05) the newborn piglets BW, while there were no differences among treatments on the suckling (day 20) and weaned (day 7) piglets BW (P > 0.05). Dietary phytogenic volatile compounds reached GL placental fluid, and milk of L and GL sows (P < 0.05). Moreover, colostrum protein in GL and milk fat content in L and GL were increased (P < 0.05). Milk of GL showed inhibitory activity against Bacillus subtilis and Staphylococcus aureus (P < 0.05). Antioxidant status of GL sows showed an enhanced (P < 0.05) of catalase (CAT) and total antioxidant capacity levels at early gestation (day 35), whereas higher levels of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) enzymes at late gestation (day 110). Likewise, GL newborn piglets showed higher CAT levels, whereas both CAT and SOD levels in suckling piglets, as well as CAT, SOD, and GSH-Px in weaned piglets, were increased in L and GL (P < 0.05). Jejunum messenger ribonucleic acid abundance of suckling piglets in L and GL groups showed overexpression of barrier function MUC2, digestive enzyme IDO, and immune response PPARGC-α, TNF-α, TGF-β1, and IL-10 genes (P < 0.05). In conclusion, dietary BPA supplementation in hyperprolific sows increased the litter size (born alive) and improved the composition and bioactivity of colostrum and milk, besides, modified the antioxidant status of sows and their offspring, as well as the suckling piglets gut health gene expression. Several BPA volatile compounds were prenatal and postnatal maternally transferred (placental fluid and milk). 10.1093/jas/skz390