加载中

    logo
    Dietary Inflammatory Index Is Related to Heart Failure Risk and Cardiac Function: A Case-Control Study in Heart Failure Patients. Moludi Jalal,Shivappa Nitin,Alisgharzadeh Soghra,Hébert James R,Alizadeh Mohammad Frontiers in nutrition Previous studies suggest that diet and inflammation are important risk factors for heart failure (HF); however, the associations remain unclear. The Dietary Inflammatory Index (DII) was established to measure the inflammatory capacity of individuals' diet. This study aimed to explore the DII in HF subjects compared with controls. We conducted a case-control (116 cases and 113 controls) study that recruited in the similar clinics. DII scores were calculated based on dietary intakes. N-Terminal pro-brain natriuretic peptide (NT-proBNP) levels and ejection fraction (EF) were assessed in both groups. In order to analyze DII scores with HF as the outcome, we used conditional logistic regression. A linear regression was applied to explore the associations between the DII and left ventricular EF (LVEF). There was statistically significant difference in DII scores in cases vs. controls (-0.16 ± 1.37 vs. -0.33 ± 1.67; = 0.040). Conditional logistic regression has shown that subjects with higher DII scores had higher risk of HF. For every one-point rise in DII score, the odds of having HF increased by 30% (OR: 1.30; CI: 1.03, 1.69; = 0.047). The EF was inversely associated with saturated fatty acid (β = -0.34, 95% CI: -0.61, -0.07; = 0.012). Subjects with higher DII scores had higher NT-proBNP levels and had lower EF. The DII score was associated with high probability of HF. It appears that consumption of anti-inflammatory diet may lead to the prevention of HF and therefore suggests that dietary modification with the goal of reducing DII scores could be a valuable strategy for improving clinical outcomes in these patients. 10.3389/fnut.2021.605396
    Association of dietary inflammatory potential with cardiometabolic risk factors and diseases: a systematic review and dose-response meta-analysis of observational studies. Aslani Zahra,Sadeghi Omid,Heidari-Beni Motahar,Zahedi Hoda,Baygi Fereshteh,Shivappa Nitin,Hébert James R,Moradi Sajjad,Sotoudeh Gity,Asayesh Hamid,Djalalinia Shirin,Qorbani Mostafa Diabetology & metabolic syndrome Context:The association of dietary inflammatory index (DII®), as an index of inflammatory quality of diet, with cardiometabolic diseases (CMDs) and risk factors (CMRFs) has been inconsistent in previous studies. Objective:The current systematic review and dose-response meta-analysis was performed to investigate the association of the DII score with CMDs and CMRFs. Data Sources:All published observational studies (cohort, case-control and cross-sectional) using PubMed/Medline, Scopus, ISI Web of Science, and Google Scholar databases were retrieved from inception through November 2019. Data extraction:Two reviewers independently extracted the data from included studies. Data analysis:Pooled hazard ratio (HR) or odds ratio (OR) were calculated by using a random-effects model. Results:Ten prospective cohort studies (total n = 291,968) with 31,069 CMDs-specific mortality, six prospective cohort studies (total n = 43,340) with 1311 CMDs-specific morbidity, two case-control studies with 2140 cases and 6246 controls and one cross-sectional study (total n = 15,613) with 1734 CMDs-specific morbidity were identified for CMDs. Meta-analyses of published observational studies demonstrated that the highest DII score category versus the lowest DII score category was associated with 29% increased risk of CMDs mortality (HR = 1.29; 95% confidence interval (CI) 1.18, 1.41). Moreover, there was a significant association between the DII score and risk of CMDs in cohort studies (HR = 1.35; 95% CI 1.13, 1.61) and non-cohort study (HR = 1.36; 95% CI 1.18, 1.57). We found a significant association between the DII score and metabolic syndrome (MetS) (OR: 1.13; 95% CI 1.03, 1.25), hyperglycemia and hypertension. None-linear dose response meta-analysis showed that there was a significant association between the DII score and risk of CMDs mortality (P < 0.001). Moreover, evidence of none-linear association between the DII score and risk of CMDs was not observed (p-value = 0.1). Conclusions:Adherence to pro-inflammatory diet was associated with increased risk of CMDs, mortality and MetS. 10.1186/s13098-020-00592-6
    Association Between Dietary Inflammatory Index and Heart Failure: Results From NHANES (1999-2018). Liu Zuheng,Liu Haiyue,Deng Qinsheng,Sun Changqing,He Wangwei,Zheng Wuyang,Tang Rong,Li Weihua,Xie Qiang Frontiers in cardiovascular medicine To explore the relationship between dietary inflammatory index (DII) and heart failure (HF) in participants with cardiovascular and cerebrovascular diseases. NHANES (1998-2018) data were collected and used to assess the association of HF with DII. Twenty-four-hour dietary consumptions were used to calculate the scores of DII. Demographic characteristics and physical and laboratory examinations were collected for the comparison between HF and non-HF groups. Logistic regression analysis and random forest analysis were performed to calculate the odds rate and determine the potential beneficial dietary components in HF. A total of 19,067 cardiac-cerebral vascular disease participants were categorized as HF ( = 1,382; 7.25%) and non-HF ( = 17,685; 92.75%) groups. Heart failure participants had higher levels of DII score compared with those in the non-HF group (0.239 ± 1.702 vs. -0.145 ± 1.704, < 0.001). Compared with individuals with T1 (DII: -3.884 to -0.570) of DII, those in T3 (DII: 1.019 to 4.598) had a higher level of total cholesterol (4.49 ± 1.16 vs. 4.75 ± 1.28 mmol/L, < 0.01), globulin (29.92 ± 5.37 vs. 31.29 ± 5.84 g/L, < 0.001), and pulse rate (69.90 ± 12.22 vs. 72.22 ± 12.77, < 0.001) and lower levels of albumin (40.76 ± 3.52 vs. 39.86 ± 3.83 g/L, < 0.001), hemoglobin (13.76 ± 1.65 vs. 13.46 ± 1.77 g/dl, < 0.05), and hematocrit (40.83 ± 4.69 vs. 40.17 ± 5.01%, < 0.05). The odds rates of HF for DII from the logistic regression were 1.140, 1.158, and 1.110 in models 1, 2, and 3, respectively. In addition, from the results of random forest analysis, dietary magnesium, fiber, and beta carotene may be essential in HF. Dietary inflammatory index was positively associated with HF in US adults, and dietary intervention might be a promising method in the therapy of HF. 10.3389/fcvm.2021.702489