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    Health policies on dialysis modality selection: a nationwide population cohort study. Lin Yi-Chun,Lin Yen-Chung,Kao Chih-Chin,Chen Hsi-Hsien,Hsu Chih-Cheng,Wu Mai-Szu BMJ open OBJECTIVES:In Taiwan, peritoneal dialysis (PD) and haemodialysis are fully accessible to patients with end-stage renal disease. However, the usage of PD is considered low in Taiwan. Since 2005, 4 major policies have been implemented by Taiwan's Ministry of Health and Welfare, namely a multidisciplinary predialysis care programme and usage increasing the PD incidence as a key performance indicator (KPI) for hospital accreditation, both of which were implemented in 2006; reimbursement of the glucose-free dialysate, icodextrin that was implemented in 2007; and insurance reimbursement for renting automated PD machines that was implemented in 2008. The aim of this study was to analyse the associations between the PD promotional policies and the actual PD selection rates. SETTING:We analysed data within the Taiwan Renal Registry Data System from 2006 to 2013, focusing on the PD incidence in relation to the timings of the 4 PD promotional policies; then we stratified the results according to age, sex and the presence of diabetes mellitus. PARTICIPANTS:From 2006 to 2013, 115 565 patients were enrolled in this study. The mean (SD) age of patients on PD was 54.6 (15.7) years. RESULTS:During the time frame in which the 4 PD promotional policies were implemented, the PD incidence increased from 12.8% in 2006 to 15.1% in 2009. The PD incidence started to decline in 2010 (13.8%) when the hospital accreditation policy was repealed. The 3 remaining policies were weakly associated with the PD incidence. The observational analysis determined that the patients' ages, sexes and diabetes mellitus incidence rates were relatively stable from 2006 to 2013. CONCLUSIONS:Of the 4 health policies intended to promote PD usage, using increasing the PD incidence as a KPI for hospital accreditation had the strongest association with the PD incidence. 10.1136/bmjopen-2016-013007
    Clinical target achievement is associated with better quality of life among dialysis patients: results from a continuous quality improvement program in a Portuguese healthcare network. Neri Luca,Ponce Pedro,Matias Nicole,Stuard Stefano,Cromm Krister Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation BACKGROUND:Patients with kidney failure have multifaced clinical needs. Continuous quality improvement (CQI) programs initiated by large healthcare provider networks bear the promise of improving guideline adherence and improving patient-centered outcome, including health-related quality of life (HRQOL). We aimed at evaluating the association between key performance indicators (KPI) adopted for our CQI and HRQOL in a large network of dialysis providers. METHODS:We conducted a survey study in 39 centers belonging to the Portuguese Fresenius Medical Care (FME) network, in September 2017. For each participant, we retrospectively extracted clinical information during the 6-month period preceding survey administration. We used this information to calculate KPI as defined by the FME-CQI policy. Those KPI were selected in the FME-CQI policy as modifiable intermediate endpoints for which previous evidence suggested a causal relationship with patients' morbidity and mortality. HRQOL was assessed by the Kidney Disease Quality of Life Short Form 36 (KDQOL-36) questionnaire. RESULTS:Among 4691 eligible patients who were invited to participate in the survey, 2263 (48.2%) answered the self-administered survey. Based on KPI standards, patients had 1.5 (± 1.2) off-target clinical parameters on average. KDQOL-36 score were generally higher than those observed in European reference population. We found a significant linear association between KPI parameters and HRQOL. This pattern was robust to adjustment for satisfaction scores. CONCLUSIONS:Our data demonstrated a graded, monotonic, dose-response relationship between the number of off-target KPIs and HRQOL. Such relationship was not mediated by patients' satisfaction and may be attributed to amelioration of disease-specific symptoms and functional capacity. 10.1007/s11136-020-02543-0
    Leveraging digital transformation to empower clinical governance: enhancement in intermediate clinical endpoints and patients' survival after implementation of a continuous quality improvement program in a large dialysis network. Garbelli Mario,Ion Titapiccolo Jasmine,Bellocchio Francesco,Stuard Stefano,Brancaccio Diego,Neri Luca Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association BACKGROUND:Treatment of end-stage kidney disease patients is extremely challenging given the inter-connected functional derangements and comorbidities characterizing the disease. Continuous Quality Improvement (CQI) in healthcare is a structured clinical governance process helping physicians adhere to best clinical practices. The digitization of patient medical records and data warehousing technologies has standardized and enhanced the efficiency of the CQ&Iacute;s evidence generation process. There is limited evidence that ameliorating intermediate outcomes would translate into better patient-centered outcomes. We sought to evaluate the relationship between Fresenius Medical Care (FME) medical patient review CQI (MPR-CQI) implementation and patients' survival in a large historical cohort study. METHODS:We included all incident adult patients with 6 months survival on chronic dialysis registered in the EMEA region between 2011-2018. We compared medical Key Performance Indicator (KPI) target achievements and 2-year mortality for patients enrolled prior and after to MPR-CQI policy onset (Cohort A and Cohort B). We adopted a structural equation model where MPR-CQI policy was the exogenous explanatory variable, KPI target achievements the mediator variable, and survival was the outcome of interest. RESULTS:4.270 patients (Cohort A: 2.397; Cohort B: 1.873) met the inclusion criteria. We observed an increase in KPI target achievements after MPR-CQI policy implementation. Mediation analysis demonstrated a significant reduction in mortality due to indirect effect of MPR-CQI implementation through improvement in KPI target achievement occurring in the post-implementation era (OR: 0.70; 95%CI: 0.65-0.76; p < 0.0001). CONCLUSIONS:Our study suggests that MPR-CQI achieved by standardized clinical practice and periodical, structured, medical patient review may improve patients' survival through improvement in medical KPIs. 10.1093/ndt/gfab160