Regional Odontodysplasia: A Systematic Review of Case Reports. Nijakowski Kacper,Woś Patryk,Surdacka Anna International journal of environmental research and public health Regional odontodysplasia is a rare developmental disorder characterised by hypoplasia and hypomineralisation of enamel and dentin. Our systematic review aimed to organise the knowledge on localisation, symptomatology and treatment methods in patients with regional odontodysplasia based on case reports published in the databases PubMed, Scopus and Web of Science. Case reports were described in 28 different countries, considering 180 patients (including 91 females). Regional odontodysplasia occurs mainly in both deciduous and permanent dentition (66.1%). The affected teeth were observed more frequently in the maxilla (70.0%), especially on the left side (45.6%). The most common reported symptoms were ghost teeth, poorly developed buds, yellowish-brown colour of crowns and delayed eruption of permanent teeth in affected quadrants. The most popular treatment method was surgical treatment (78.6%) with subsequent prosthetic therapy (34.6%). Based on the review of cases, pathognomonic clinical and radiological signs can be found, however, it is difficult to reach a consensus on the choice of treatment method. 10.3390/ijerph19031683

Idiopathic failure of eruption of multiple permanent teeth: report of 2 adults with a highlight on molecular biology. Sivakumar Arunachalam,Valiathan Ashima,Gandhi Sumit,Mohandas Ashil A American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics Multiple unerupted teeth with no obvious etiology is a rare dental anomaly. Various local and systemic factors have been implicated in the failure of eruption of multiple permanent teeth. But the localization of the genetic defect in the phenotype of failure of eruption is largely unknown at present. Our aims in this article were to consolidate and organize the available information regarding the molecular biology of tooth eruption and to corroborate the current evidence with the report of 2 adult cases of failure of eruption of multiple permanent teeth without a known cause. 10.1016/j.ajodo.2006.04.034

Idiopathic multiple impacted unerupted teeth: Case report and discussion. Sujatha G,Sivapathasundharam B,Sivakumar G,Nalinkumar S,Ramasamy M,Prasad T Srinivasa Journal of oral and maxillofacial pathology : JOMFP Multiple impacted permanent teeth are usually related to syndromes, metabolic and hormonal disorders. However, in some cases, impaction of multiple teeth is not associated with any syndrome. In this report, we present a case of 17-year-old male patient with missing teeth. Radiographs revealed multiple impacted permanent teeth, though medical and family history along with physical examination was not suggestive of any syndromes. If other investigations are negative, an idiopathic case of multiple impacted teeth is suggested to be the possible diagnosis. The objective of this report is to increase awareness of such cases especially in the absence of hereditary/genetic/metabolic factors usually inherent in such scenarios. The patient management in such cases needs to be planned specifically from a multidisciplinary standpoint. 10.4103/0973-029X.92989

Management of a rare case of idiopathic multiple unerupted impacted permanent teeth in an adult female patient. Shetty Karunakar,Kumar Mahesh,Amanna Susan,Sridharan Srirangarajan,Reddy Satyanarayan Journal of Indian Prosthodontic Society This clinical case report describes the multi-disciplinary approach in the management of an unusual presentation of idiopathic multiple unerupted impacted permanent teeth in a 20-year-old female patient. The case was unique in that, not only were there multiple missing permanent teeth, but also over retained deciduous teeth and attrited existing permanent teeth with loss of vertical dimension of occlusion. Since the patient was young, it was decided to retain all the erupted permanent teeth and extract the infected deciduous teeth with the objective of fabricating overlay complete dentures. This is a simple, reversible and an economical treatment modality, which satisfies both the esthetic and functional demands where the extraction of teeth is not generally indicated and, in addition, provides a stable occlusion. 10.4103/0972-4052.161572