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    A 7-year follow-up study on untreated deep or mixed facial infantile hemangioma in East-Asian patients: When propranolol was not yet an option. Chang Shih-Jen,Qiao Congzhen,Chang Lei,Gao Wei,Jin Yunbo,Ma Gang,Qiu Yajing,Lin Xiaoxi The Journal of dermatology Infantile hemangioma (IH) is a type of benign tumor that develops during infancy and spontaneously involutes after 1 year of age. Before the introduction of propranolol in 2008, some patients with IH were instructed to wait for the involution without treatment. This long-term follow-up study was conducted to assess the prognosis of East-Asian children with untreated deep or mixed facial IH. Skin sequelae were assessed by comparing images obtained during the patients' first and last visits in our clinic. Possible factors were assessed for their association with IH prognosis. The mean follow-up time was 7.4 years. Among the 48 patients with deep or mixed facial IH, 26 (54%) achieved complete involution without sequelae and 22 encountered various sequelae, including telangiectasia (36.3%), fibrofatty residue (68.2%), and scars (4%). The complete regression rate of deep or mixed IH occurring in the central facial region was significantly lower than for those in the perifacial region (33.3% vs 66.7%, respectively, χ , P = 0.025). Further, the most common sequelae in this area are fibrofatty residue. 10.1111/1346-8138.15080
    Comparison of the efficacy between topical timolol and pulsed dye laser in the treatment of ulcerated infantile haemangiomas: a randomized controlled study. Chen Q Y,Chang L,Qiu Y J,Ying H R,Chang S J,Zhang Y,Chen Z A,Ma G,Lin X X Journal of the European Academy of Dermatology and Venereology : JEADV 10.1111/jdv.17057
    Liposuction for large facial involuted infantile hemangiomas in children: clinical evaluation and management strategies. The Journal of dermatological treatment BACKGROUND:Large involuted infantile hemangioma (IH) can cause facial disfigurement and functional impairment and constitute a major concern to children and parents. Liposuction for large involuted IH has been reported in some case reports. However, systematic study is seldom and the patient outcome is uneven. METHODS:Thirteen eligible patients who underwent liposuction treatment at Shanghai Ninth People's Hospital between August 2016 and August 2018 were reviewed. IH lesions were evaluated according to their timing, components, involvement, and location. Liposuction was performed to address the volumetric residue. RESULTS:Between August 2016 and August 2018, 13 patients, four boys and nine girls, with an average age of 8 ± 4.4 years underwent the liposuction for large facial involuted IH. Clinical follow-up ranges from 3 to 18 months. In two cases, lipectomy and facelift were undertaken in conjunction with liposuction. One patient needs a secondary revision due to the residual facial asymmetry. All patients were satisfied with the outcomes. CONCLUSIONS:Liposuction for large involuted IH is reliable and underreported in the literature. With proper patient evaluation and good counseling on realistic expectations, liposuction for large facial involuted IH can be expected to achieve excellent results with a low complication rate in pediatric population. 10.1080/09546634.2019.1687816
    Forehead deformities after tissue expansion: Retrospective analysis and recommendations. Qiu Yajing,Qiao Congzhen,Yang Jingyan,Jin Yunbo,Chen Hui,Lin Xiaoxi Journal of plastic, reconstructive & aesthetic surgery : JPRAS BACKGROUND:Tissue expanders can lead to bone deformity as well as bone resorption. Not all changes in the cranial bone can be completely normalised after tissue expander extraction. This study aimed to investigate the potential factors for persistent forehead deformities after tissue expansion. PATIENTS AND METHODS:Cases of forehead tissue expansion performed from 2011 to 2015 were retrospectively reviewed. Demographic and clinical data were collected. Two plastic surgeons (Y.Q. and C.Q.) evaluated changes in the forehead by comparing preoperative and most recent postoperative photographs. The Fisher exact, chi-square and Student t tests, and univariate and multivariate logistic regression analyses were performed in this study. RESULTS:Sixty-seven patients underwent forehead expanded flap reconstructions and continuous follow-ups were done in the outpatient service. The mean duration of the follow-ups after expander removal was 33.86 months. Overall, 28 (41.8%) patients had forehead changes. Age, sex, indications for tissue expansion and follow-up time were not associated with forehead changes. There were significant differences in the total injection volume and expansion period between patients with forehead changes (41.8%) and those without (58.2%). No significant negative correlation was found between the duration of pressure bandage usage post-operatively and the occurrence of forehead changes. CONCLUSIONS:Our recommendations for performing tissue expansion in the skull area are as follows: (1) always choose expanders with the largest base dimension; (2) perform tissue expansion as quickly as possible and (3) do not cause overexpansion. In addition, there was no proven benefit of using pressure bandages when skeletal changes occurred. 10.1016/j.bjps.2019.09.020
    Successful treatment of infantile hemangioma with high risk of severe sequelae by microneedle radiofrequency. Qiu Yajing,Qiao Congzhen,Yang Jingyan,Gao Wei,Lin Xiaoxi Dermatologic therapy 10.1111/dth.13953
    Cable-Stayed Face Lift: An Innovative Short-Scar Lift for Better Correction of Nasolabial Folds in East Asians. Qiu Yajing,Gao Wei,Yang Jingyan,Jin Yunbo,Zou Yun,Qiao Congzhen,Chen Hui,Lin Xiaoxi Plastic and reconstructive surgery BACKGROUND:The improvement of nasolabial folds by either lateral superficial musculoaponeurotic system rhytidectomy or minimal access cranial suspension lift alone is commonly performed, but patient satisfaction is often limited in East Asians. An innovative technique, termed the cable-stayed face lift, which combines the strengths of lateral superficial musculoaponeurotic system rhytidectomy and minimal access cranial suspension lift, was developed for improved results. METHODS:Between 2016 and 2019, 20 cable-stayed face lifts were performed in a single hospital. Two plastic surgeons independently evaluated postsurgery outcomes using a five-point Likert scale, where 5 = excellent, 4 = good, 3 = fair, 2 = no change, and 1 = worse. Patient satisfaction was assessed by relevant items from the FACE-Q questionnaire. RESULTS:Twenty patients with a mean age of 51 years underwent face-lift surgery. The mean follow-up ± SD was 11.3 ± 9.8 months. The five-point Likert scale score evaluated by surgeons was 3.65 ± 1.08. Patient-perceived age visual analogue scale (7.8 ± 4.4) exhibited a difference between preoperative actual age and postoperative apparent age. Patients demonstrated high satisfaction with outcome (67.5 ± 16.2) and satisfaction with lower face and jawline (76.2 ± 14.9). No major complication, hematoma, or seroma was observed. CONCLUSION:The authors' approach-cable-stayed face lift-offers a good alternative to provide a more effective effacement of nasolabial folds, by lifting the nasolabial folds with parallel vector and lower face and neck with the vertical vector. CLINICAL QUESTION/LEVEL OF EVIDENCE:Therapeutic, IV. 10.1097/PRS.0000000000008219
    Repair of a Total Defect in the Upper Lateral and Medial Lip. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 10.1097/DSS.0000000000003043
    One-Stage Reconstruction of Large Upper Vermillion Defects Using a Lower to Upper Bipedicle Axial Cross-Lip Vermillion Flap. Annals of plastic surgery BACKGROUND:Vermilion deformities after intralesional bleomycin A5 injections for hemangiomas of the upper lip have not been rare during the past 2 decades in China. In this article, we summarized our 10 years of experience using a lower to upper axial cross-lip musculomucosal flap with bipedicle lower labial coronary arteries for 1-stage reconstruction of large upper vermillion defects. Based on several years of experience, we also created some modified approaches to achieve satisfactory cosmetic outcomes. PATIENTS AND METHODS:From July 2006 to July 2016, a total of 25 patients with moderate and severe vermilion defects of the upper lip were treated with this method at the Department of Plastic and Reconstructive Surgery in Shanghai Ninth People's Hospital. The cosmetic outcomes and complications were reviewed. RESULTS:The overall mean follow-up time was 14.9 months. No patients had infection or hematoma. All the flaps survived, and all the patients were satisfied with the postoperative appearance. CONCLUSIONS:Our experience has proven that a lower to upper axial cross-lip musculomucosal flap with bipedicle lower labial coronary arteries is a safe and effective approach for correcting large upper vermillion defects. It is a 1-stage operation for the overall length of upper vermillion reconstruction. This method could improve upper-lip aesthetics and achieve reconstructive goals while avoiding lower-lip deformities. 10.1097/SAP.0000000000003218